There are multiple origins and meanings for the name:
1. Persian name (رکسانا) meaning - "brightness, brilliance, bright, intensity, illumination"
2. Form of the given name Roxelana=Roxana + Alana="bright Aryan"
Roxana (Roxanne, Roxandra, Roxane) was a Bactrian princess and a wife of Alexander the Great. She was born earlier than the year 343 BC, though the precise date remains uncertain.